Once farmland, University City’s original 85 acres were purchased in 1902 by Edward Gardner Lewis for his publishing headquarters, with future plans to develop the area into a “high-class residential district” and a model “City Beautiful.” The city’s population quadrupled during the 1920s, and in 1927 Cyrus Walbridge Merrell, a former executive with the J.S. Merrell Drug Co., decided to build his home in a newly formed subdivision.

